Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 18/20 | 0.55 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25586729 | 0.88 | RIPK1 (0.56) | RIPK1GRM5 | |
| SCHEMBL25586414 | 0.87 | RIPK1 (0.44) | RIPK1 | |
| SCHEMBL23085493 | 0.85 | RIPK1 (0.65) | RIPK1 | |
| SCHEMBL29271479 | 0.84 | RIPK1 (0.44) | RIPK1 | |
| Hydrochloric Acid SCHEMBL30986682 | 0.83 | RIPK1 (0.44) | RIPK1 | |
| SCHEMBL24076721 | 0.82 | RIPK1 (0.56) | RIPK1 | |
| SCHEMBL24076698 | 0.82 | TDP1 (0.44) | RIPK1 | |
| SCHEMBL24076700 | 0.81 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL22968464 | 0.80 | RIPK1 (0.54) | RIPK1 | |
| SCHEMBL25587241 | 0.80 | GRM5 (0.45) | RIPK1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138317-A1 | COMPOUND HAVING RIPK1 INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-07-27 | — | — | WO | disclosed |