SCHEMBL25878965

SCHEMBL25878965

OC1(c2cc(Cl)ccc2-c2ccccc2)C2CC3CC(C2)CC1C3

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.42
HSD11B1 P28845 4/20 0.39
FABP4 P15090 4/20 0.37
FABP5 Q01469 1/20 0.36
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
ALB P02768 1/20 0.35
KMT2A Q03164 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.34
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23627502 0.91 PDK2 (0.42) PDK2HSD11B1CNR2
SCHEMBL24627269 0.91 PDK2 (0.38) PDK2HSD11B1FABP4FABP5MEN1
SCHEMBL25878966 0.89 PDK2 (0.42) PDK2HSD11B1FABP4FABP5MEN1
SCHEMBL24316404 0.87 KMT2A (0.37) PDK2HSD11B1FABP4MEN1LMNA
SCHEMBL25962012 0.85 PDK2 (0.46) PDK2HSD11B1FABP4FABP5MEN1
SCHEMBL24618107 0.84 PDK2 (0.48) PDK2HSD11B1LMNA
SCHEMBL25501493 0.84 PDK2 (0.45) PDK2HSD11B1CNR2
SCHEMBL25501503 0.82 PDK2 (0.39) PDK2HSD11B1CNR2
SCHEMBL25818601 0.82 AHR (0.36) PDK2MEN1LMNAKMT2A
SCHEMBL25501497 0.82 PDK2 (0.44) PDK2HSD11B1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM PDK2 639/4885HSD11B1 3861/4885FABP4 3651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.