SCHEMBL2587905

SCHEMBL2587905

CCOC(=O)C(OC)Oc1ncccc1Oc1cc(-c2c(C(F)(F)F)n(C)c(=O)[nH]c2=O)c(F)cc1Cl

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 19/20 0.37
DRD5 P21918 1/20 0.36
KMO O15229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2591656 0.94 DRD1 (0.37) DRD1DRD5KMO
SCHEMBL2591602 0.90 BCAT2 (0.34)
SCHEMBL18614679 0.88 DRD1 (0.40) DRD1DRD5
SCHEMBL2587959 0.87 BRD4 (0.32)
SCHEMBL2584788 0.85 BCAT2 (0.33)
SCHEMBL18894374 0.84 DRD1 (0.39) DRD1DRD5KMO
SCHEMBL2589268 0.84 BCAT2 (0.33)
SCHEMBL2588542 0.83 MEN1 (0.31)
SCHEMBL2584490 0.83 BCAT2 (0.33) DRD1DRD5
SCHEMBL2587115 0.83 BCAT2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011137088-A1 HERBICIDAL URACILS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-03 WO disclosed