SCHEMBL25879057

SCHEMBL25879057

Clc1cccc2c1-c1ccc(-c3nc(-c4ccccc4)c4ccccc4n3)cc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
WHR1 P49842 1/20 0.35
NR1I3 Q14994 1/20 0.33
GBA1 P04062 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
MAPK1 P28482 2/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.32
ALDH1A1 P00352 3/20 0.32
PDE5A O76074 3/20 0.32
KDM4E B2RXH2 2/20 0.32
AKT1 P31749 1/20 0.32
AKT2 P31751 1/20 0.32
USP2 O75604 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C19 P33261 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25896221 0.88 MEN1 (0.33) ATMMEN1KMT2AWHR1NR1I3
SCHEMBL25038030 0.83 MEN1 (0.45) ATMMEN1KMT2AWHR1NR1I3
SCHEMBL25878702 0.83 MEN1 (0.34) ATMMEN1KMT2AWHR1GBA1
SCHEMBL30593272 0.82 PDK2 (0.39) PTPN11PTPRCAP
SCHEMBL24622732 0.82 MEN1 (0.39) ATMMEN1KMT2AWHR1GBA1
SCHEMBL25879056 0.81 PTPN11 (0.32) PTPN11PTPRCAP
SCHEMBL25879060 0.81 PDK2 (0.38) PTPN11PTPRCAP
SCHEMBL25035974 0.80 MEN1 (0.37) ATMMEN1KMT2AWHR1GBA1
SCHEMBL24622633 0.80 MEN1 (0.39) ATMMEN1KMT2AWHR1GBA1
SCHEMBL25879055 0.79 PDK2 (0.32) PTPN11PTPRCAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ATM 1153/4885MEN1 2884/4885KMT2A 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.