Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25878968 | 0.90 | RIPK1 (0.68) | RIPK1 | |
| SCHEMBL25879119 | 0.85 | RIPK1 (0.61) | RIPK1 | |
| SCHEMBL25879419 | 0.84 | RIPK1 (0.77) | RIPK1 | |
| SCHEMBL25879172 | 0.84 | RIPK1 (0.61) | RIPK1 | |
| SCHEMBL25879123 | 0.83 | RIPK1 (0.56) | RIPK1 | |
| SCHEMBL25879171 | 0.83 | RIPK1 (0.70) | RIPK1 | |
| SCHEMBL25879049 | 0.82 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL25879300 | 0.81 | RIPK1 (0.71) | RIPK1 | |
| SCHEMBL25878876 | 0.81 | RIPK1 (0.61) | RIPK1 | |
| SCHEMBL25878969 | 0.81 | RIPK1 (0.61) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138317-A1 | COMPOUND HAVING RIPK1 INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-07-27 | — | — | WO | disclosed |