Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.43 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25315795 | 0.92 | EPHX2 (0.47) | EPHX2EPHX1HSD11B1POLBMAPT | |
| SCHEMBL25311831 | 0.91 | EPHX2 (0.44) | EPHX2EPHX1PRKAA2MAPTPRKAB2 | |
| SCHEMBL25878961 | 0.85 | LANCL2 (0.62) | HSD11B1USP30MAPTRXFP1MEN1 | |
| SCHEMBL25312498 | 0.85 | MAPT (0.53) | HSD11B1POLBMAPTMEN1KMT2A | |
| SCHEMBL25310693 | 0.84 | GNE (0.45) | EPHX2HSD11B1MAPTMEN1KMT2A | |
| SCHEMBL30471249 | 0.84 | NAMPT (0.52) | EPHX2USP30MEN1KMT2A | |
| SCHEMBL25883636 | 0.84 | NAMPT (0.52) | EPHX2USP30MEN1KMT2A | |
| SCHEMBL25878265 | 0.82 | MAPT (0.42) | HSD11B1POLBUSP30MAPTRXFP1 | |
| SCHEMBL25879044 | 0.82 | EPHX2 (0.47) | EPHX2EPHX1PRKAA2POLBMEN1 | |
| SCHEMBL25311390 | 0.81 | GNE (0.49) | HSD11B1POLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |