Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310088 | 0.92 | MAPT (0.43) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL25310085 | 0.92 | MAPT (0.43) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL25883212 | 0.91 | AURKA (0.44) | MAPTRAB9AAURKAAURKB | |
| SCHEMBL25882715 | 0.85 | MEN1 (0.44) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL25311732 | 0.85 | LANCL2 (0.57) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL29466326 | 0.85 | MEN1 (0.49) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL25878262 | 0.85 | MEN1 (0.49) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL29466310 | 0.84 | ANO1 (0.44) | KDM4EUSP30 | |
| SCHEMBL25879144 | 0.82 | EPHX2 (0.46) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL25311803 | 0.81 | MAPT (0.45) | MAPTMEN1KMT2AKDM4EALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |