⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25879616 | 0.88 | INMT (0.32) | — | |
| SCHEMBL25892906 | 0.67 | INMT (0.32) | — | |
| SCHEMBL26726045 | 0.65 | — | — | |
| SCHEMBL1698643 | 0.65 | — | — | |
| SCHEMBL21859351 | 0.65 | — | — | |
| SCHEMBL13472021 | 0.62 | INMT (0.30) | — | |
| SCHEMBL25879618 | 0.61 | PIK3CD (0.33) | — | |
| SCHEMBL25879549 | 0.61 | JAK2 (0.30) | — | |
| SCHEMBL25879613 | 0.61 | INMT (0.30) | — | |
| SCHEMBL25879620 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | US | disclosed |
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | US | disclosed |