Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25877375 | 0.94 | LANCL2 (0.86) | LANCL2MEN1KMT2AHRH4RAB9A | |
| SCHEMBL29466338 | 0.94 | LANCL2 (0.86) | LANCL2MEN1KMT2AHRH4RAB9A | |
| SCHEMBL25314181 | 0.89 | LANCL2 (0.79) | LANCL2MEN1KMT2AHRH4ATR | |
| SCHEMBL25312093 | 0.89 | LANCL2 (0.79) | LANCL2MEN1KMT2AHRH4RAB9A | |
| SCHEMBL29466288 | 0.89 | LANCL2 (0.79) | LANCL2MEN1KMT2AHRH4ATR | |
| SCHEMBL25877794 | 0.89 | LANCL2 (0.82) | LANCL2MEN1KMT2AHRH4RAB9A | |
| Omilancor SCHEMBL17706588 | 0.87 | LANCL2 (1.00) | LANCL2MEN1KMT2AHRH4RAB9A | |
| Omilancor SCHEMBL29349469 | 0.87 | LANCL2 (1.00) | LANCL2MEN1KMT2AHRH4RAB9A | |
| SCHEMBL25881521 | 0.85 | LANCL2 (0.76) | LANCL2MEN1KMT2AHRH4SMN1; SMN2 | |
| SCHEMBL25881551 | 0.84 | LANCL2 (0.74) | LANCL2MEN1KMT2AHRH4ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |