Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.79 |
| ▸ | GABRD | O14764 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25314181 | 1.00 | LANCL2 (0.79) | LANCL2GABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL25877375 | 0.96 | LANCL2 (0.86) | LANCL2MEN1KMT2AATRHRH4 | |
| SCHEMBL29466338 | 0.96 | LANCL2 (0.86) | LANCL2MEN1KMT2AATRHRH4 | |
| SCHEMBL25881551 | 0.95 | LANCL2 (0.74) | LANCL2GABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL25881624 | 0.92 | LANCL2 (0.69) | LANCL2GABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL25312093 | 0.91 | LANCL2 (0.79) | LANCL2MEN1KMT2AATRCYP1A2 | |
| SCHEMBL25877794 | 0.91 | LANCL2 (0.82) | LANCL2MEN1KMT2AATRHRH4 | |
| SCHEMBL17705594 | 0.90 | LANCL2 (0.88) | LANCL2MEN1KMT2AATRHRH4 | |
| SCHEMBL25879755 | 0.89 | LANCL2 (0.76) | LANCL2MEN1KMT2AATRHRH4 | |
| SCHEMBL25881745 | 0.89 | LANCL2 (0.71) | LANCL2MEN1KMT2AATRHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195780-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195806-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |