Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 3/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | FPR3 | P25089 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13734537 | 0.86 | LOX (0.54) | LOXLOXL2CDK2GSK3BALDH1A1 | |
| SCHEMBL25880555 | 0.84 | KLKB1 (0.46) | LOXLOXL2RECQLNR3C2CYP2C9 | |
| SCHEMBL19049394 | 0.84 | LOX (0.51) | LOXLOXL2CDK2GSK3BALDH1A1 | |
| SCHEMBL25880800 | 0.81 | RECQL (0.42) | LOXLOXL2CDK2GSK3BRECQL | |
| SCHEMBL25880968 | 0.81 | RECQL (0.42) | LOXLOXL2RECQLNR3C2CYP2C9 | |
| SCHEMBL2788201 | 0.81 | KDM5C (0.49) | LOXLOXL2CDK2GSK3BMMP13 | |
| SCHEMBL18997629 | 0.81 | HPGD (0.51) | LOXLOXL2CDK2GSK3BALDH1A1 | |
| SCHEMBL19002539 | 0.81 | EPHX2 (0.49) | LOXLOXL2CDK2GSK3BALDH1A1 | |
| SCHEMBL31174780 | 0.81 | RECQL (0.40) | LOXLOXL2CDK2GSK3BRECQL | |
| SCHEMBL25639248 | 0.81 | RECQL (0.40) | LOXLOXL2CDK2GSK3BRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121992-A1 | CYCLOPROPYL COMPOUNDS | ICAGEN, LLC (US) | 2023-06-29 | — | — | WO | disclosed |