Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | LOX | P28300 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569972 | 0.85 | EPHX2 (0.45) | RECQLNR3C2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL22324220 | 0.85 | EPHX2 (0.45) | RECQLNR3C2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL31481235 | 0.81 | GABRP (0.41) | NR3C2LOXL2LOXAURKA | |
| SCHEMBL25880602 | 0.81 | LOX (0.57) | RECQLNR3C2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL25880968 | 0.81 | RECQL (0.42) | RECQLNR3C2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL25880834 | 0.80 | RECQL (0.41) | RECQLNR3C2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL31424999 | 0.78 | LOXL2 (0.57) | RECQLNR3C2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL25638990 | 0.78 | LOXL2 (0.57) | RECQLNR3C2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL25880555 | 0.78 | KLKB1 (0.46) | RECQLNR3C2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL31174780 | 0.77 | RECQL (0.40) | RECQLNR3C2CYP2C9CYP2C19LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121992-A1 | CYCLOPROPYL COMPOUNDS | ICAGEN, LLC (US) | 2023-06-29 | — | — | WO | disclosed |