Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310936 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25882701 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25310339 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25880948 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25311377 | 0.76 | KDM4E (0.62) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL19322175 | 0.74 | KDM4E (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25878144 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25877650 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25311112 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25878977 | 0.71 | KDM4E (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |