Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25311588 | 0.89 | RAB9A (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL25311960 | 0.89 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL29484624 | 0.89 | RAB9A (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL25311377 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL25311112 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL29484616 | 0.85 | NAMPT (0.49) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL25880869 | 0.85 | NAMPT (0.49) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL19322175 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL29466339 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL28709673 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |