Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 7/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 6/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77518 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL17327517 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL19735717 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL5410915 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL24584612 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL20524278 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL23330709 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL2723648 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL502378 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR | |
| SCHEMBL13396023 | 1.00 | CYP2D6 (0.70) | CYP2D6THRBHSD17B10CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530233-B2 | Beta-nicotinate ester nucleotides and processes for preparing same | CORNELL UNIVERSITY (US) | 2022-12-20 | — | — | US | claimed |
| CN-110709406-B | Beta-nicotinate nucleotide and preparation method thereof | 康奈尔大学 | 2022-11-08 | — | — | CN | claimed |
| US-20210388018-A1 | METHYL AND ETHYL NICOTINATE-RIBOSIDE-5-PHOSPHATES, PREPARATION THEREOF AND METHODS OF USE THEREOF | CORNELL UNIVERSITY (US) | 2021-12-16 | — | — | US | claimed |
| US-20210214386-A1 | BETA-NICOTINATE ESTER NUCLEOTIDES AND PROCESSES FOR PREPARING SAME | CORNELL UNIVERSITY (US) | 2021-07-15 | — | — | US | claimed |
| EP-3606929-B1 | BETA-NICOTINATE ESTER NUCLEOTIDES AND PROCESSES FOR PREPARING SAME | UNIV CORNELL (US) | 2021-06-02 | — | — | EP | claimed |
| US-10961268-B2 | β-nicotinate ester nucleotides and process for preparing same | CORNELL UNIVERSITY (US) | 2021-03-30 | — | — | US | claimed |
| EP-3606929-A1 | BETA-NICOTINATE ESTER NUCLEOTIDES AND PROCESSES FOR PREPARING SAME | Cornell University (US) | 2020-02-12 | — | — | EP | claimed |
| US-20200031860-A1 | BETA-NICOTINATE ESTER NUCLEOTIDES AND PROCESS FOR PREPARING SAME | CORNELL UNIVERSITY (US) | 2020-01-30 | — | — | US | claimed |
| CN-110709406-A | Beta-nicotinate nucleotide and preparation method thereof | 康奈尔大学 | 2020-01-17 | — | — | CN | claimed |
| WO-2018187540-A1 | BETA-NICOTINATE ESTER NUCLEOTIDES AND PROCESSES FOR PREPARING SAME | CORNELL UNIVERSITY (US) | 2018-10-11 | — | — | WO | claimed |
| US-9266863-B2 | Process for the synthesis of azacitidine and decitabine | CHEMI SPA (IT) | 2016-02-23 | — | — | US | claimed |
| EP-2371825-B1 | Process for the synthesis of azacitidine and decitabine | CHEMI SPA (IT) | 2014-01-08 | — | — | EP | claimed |
| US-20110245485-A1 | PROCESS FOR THE SYNTHESIS OF AZACITIDINE AND DECITABINE | CHEMI SPA (IT) | 2011-10-06 | — | — | US | claimed |
| EP-2371825-A1 | Process for the synthesis of azacitidine and decitabine | Chemi SPA (IT) | 2011-10-05 | — | — | EP | claimed |
| WO-2003002586-A1 | [4-(4-CYANOBENZOYL)PHENYL]GLYCOFURANOSIDE DERIVATIVES, USE OF SAID DERIVATIVES AS A MEDICAMENT, PRODUCTION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRES FOURNIER SA (FR) | 2003-01-09 | — | — | WO | claimed |
| US-4914233-A | Synthesis of beta-thymidine | ETHYL CORPORATION (US) | 1990-04-03 | — | — | US | claimed |
| JP-2292297-A | — | — | None | — | — | JP | disclosed |
| EP-4744667-A2 | EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF | The Queen's University Of Belfast (GB) | 2026-05-20 | — | — | EP | disclosed |
| US-4056674-A | VIRICIDE, BACTERICIDE | ICN PHARMACEUTICALS, INC. (US) | 1977-11-01 | — | — | US | disclosed |
| US-3954752-A | Process for preparing 2',3',5'-tri-0-acetyl-6-azauridine | CESKOSLOVENSKA AKADEMIE VED (CS) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961268-B2 | β-nicotinate ester nucleotides and process for preparing same | NAPRT, NAMPT, NNT | CYP2D6 1338/4885THRB 1033/4885HSD17B10 1442/4885 |
| US-20110245485-A1 | PROCESS FOR THE SYNTHESIS OF AZACITIDINE AND DECITABINE | DNMT1, TET1, TET2 | CYP2D6 969/4885THRB 3467/4885HSD17B10 3882/4885 |
| US-20210214386-A1 | BETA-NICOTINATE ESTER NUCLEOTIDES AND PROCESSES FOR PREPARING SAME | NAPRT, NAMPT, NNT | CYP2D6 1499/4885THRB 1053/4885HSD17B10 1588/4885 |
| US-20200031860-A1 | BETA-NICOTINATE ESTER NUCLEOTIDES AND PROCESS FOR PREPARING SAME | NAPRT, NAMPT, NNT | CYP2D6 1543/4885THRB 1031/4885HSD17B10 1525/4885 |
| US-11530233-B2 | Beta-nicotinate ester nucleotides and processes for preparing same | NAPRT, NAMPT, NNT | CYP2D6 1499/4885THRB 1053/4885HSD17B10 1588/4885 |
| US-20210388018-A1 | METHYL AND ETHYL NICOTINATE-RIBOSIDE-5-PHOSPHATES, PREPARATION THEREOF AND METHODS OF USE THEREOF | NNT, NME4, NADK | CYP2D6 2514/4885THRB 4035/4885HSD17B10 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.