Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.57 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.57 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.52 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26152831 | 0.89 | PARP1 (0.72) | PARP1PARP2 | |
| SCHEMBL25889656 | 0.88 | PARP1 (0.60) | PARP1PARP2TNK2TNK1 | |
| SCHEMBL25889859 | 0.83 | PARP1 (0.62) | PARP1PARP2 | |
| SCHEMBL25605346 | 0.80 | PARP1 (0.59) | PARP1PARP2 | |
| SCHEMBL25889585 | 0.79 | PARP1 (0.58) | PARP1PARP2 | |
| SCHEMBL25889855 | 0.79 | PARP1 (0.65) | PARP1PARP2 | |
| SCHEMBL25919221 | 0.79 | PARP1 (0.56) | PARP1PARP2 | |
| SCHEMBL25889854 | 0.79 | PARP1 (0.69) | PARP1PARP2 | |
| SCHEMBL30414729 | 0.78 | PARP1 (0.47) | PARP1PARP2TNK2TNK1 | |
| SCHEMBL25919915 | 0.78 | PARP1 (0.61) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234952-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234952-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. | 2023-07-27 | — | — | US | disclosed |
| WO-2023141290-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. (US) | 2023-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234952-A1 | PARP1 INHIBITORS AND USES THEREOF | PARP1, PARP11, PARP12 | PARP1 1/4885PARP2 5/4885TNK2 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.