Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622907 | 0.89 | ADRB1 (0.39) | ADRB1DHFRGRM2HTR7MAPT | |
| SCHEMBL25897797 | 0.84 | MAPT (0.50) | GRM2HTR7MAPTNPSR1ALDH1A1 | |
| SCHEMBL25890151 | 0.81 | ADRB1 (0.36) | ADRB1MAPTNPSR1ALDH1A1RAB9A | |
| SCHEMBL25900775 | 0.81 | ACACB (0.38) | AR | |
| SCHEMBL19012627 | 0.80 | ADRB1 (0.40) | ADRB1DHFRGRM2HTR7MAPT | |
| SCHEMBL25890153 | 0.79 | ATM (0.36) | ADRB1HTR7MAPTNPSR1ALDH1A1 | |
| SCHEMBL6622268 | 0.74 | KMT2A (0.51) | ADRB1GRM2KMT2AGAA | |
| SCHEMBL24824178 | 0.72 | ADRB1 (0.47) | ADRB1HTR7MEN1KMT2AGAA | |
| SCHEMBL26326862 | 0.72 | ADRB1 (0.47) | ADRB1HTR7MAPTMEN1KMT2A | |
| SCHEMBL25890156 | 0.72 | MAPT (0.40) | ADRB1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |