Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25892408 | 1.00 | CHRM1 (0.55) | CHRM1CHRM2CHRM3USP2SMN1; SMN2 | |
| SCHEMBL18235300 | 0.81 | CHRM1 (0.60) | CHRM1CHRM2CHRM3USP2SMN1; SMN2 | |
| SCHEMBL1088712 | 0.80 | USP2 (0.62) | USP2SMN1; SMN2RECQLTHRBGAA | |
| SCHEMBL25318233 | 0.79 | GLA (0.42) | CHRM1SMN1; SMN2THRBGAA | |
| SCHEMBL25318229 | 0.79 | GLA (0.42) | CHRM1SMN1; SMN2THRBGAA | |
| SCHEMBL18497398 | 0.78 | USP2 (0.59) | USP2SMN1; SMN2RECQLTHRBNR1H2 | |
| SCHEMBL18497380 | 0.77 | RECQL (0.56) | USP2SMN1; SMN2RECQLTHRBNR1H2 | |
| SCHEMBL18497381 | 0.77 | RECQL (0.56) | USP2SMN1; SMN2RECQLTHRBNR1H2 | |
| SCHEMBL12094625 | 0.77 | CHRM2 (0.68) | CHRM1CHRM2CHRM3PREPHSD11B1 | |
| SCHEMBL24448818 | 0.77 | CHRM1 (0.68) | CHRM1CHRM2CHRM3PREPHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141323-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-07-27 | — | — | WO | disclosed |