Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25318233 | 1.00 | GLA (0.42) | GLAHSD17B10THRBKDM4EHRH3 | |
| SCHEMBL25892408 | 0.79 | CHRM1 (0.55) | THRBCHRM1GAASMN1; SMN2 | |
| SCHEMBL25890494 | 0.79 | CHRM1 (0.55) | THRBCHRM1GAASMN1; SMN2 | |
| SCHEMBL19971640 | 0.74 | HSD17B10 (0.41) | GLAHSD17B10THRBKDM4EHRH3 | |
| SCHEMBL18579016 | 0.73 | HSD17B10 (0.46) | GLAHSD17B10THRBKDM4EALOX15 | |
| SCHEMBL25890504 | 0.72 | HRH3 (0.38) | THRBKDM4EHRH3ALDH1A1GAA | |
| SCHEMBL18497552 | 0.72 | THRB (0.48) | GLAHSD17B10THRBKDM4EALOX15 | |
| SCHEMBL18497550 | 0.72 | THRB (0.48) | GLAHSD17B10THRBKDM4EALOX15 | |
| SCHEMBL25318878 | 0.72 | GLA (0.40) | GLAHSD17B10KDM4EHRH3ALOX15 | |
| SCHEMBL25429489 | 0.72 | GLA (0.40) | GLAHSD17B10KDM4EHRH3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141323-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-07-27 | — | — | WO | disclosed |