SCHEMBL2589245

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7497434	0.88	PIM3 (0.55)	NR4A2PIM3PIM1NUDT1CREBBP
	SCHEMBL12565533	0.87	NR4A2 (0.49)	NR4A2PIM3PIM1NUDT1CREBBP
	SCHEMBL2588280	0.82	PIM3 (0.50)	NR4A2PIM3PIM1CREBBPKDM4E
	SCHEMBL22587514	0.82	PIM3 (0.50)	NR4A2PIM3PIM1NUDT1CREBBP
	SCHEMBL6315440	0.82	NR4A2 (0.61)	NR4A2PIM3PIM1NUDT1CREBBP
	SCHEMBL31480354	0.82	PIM3 (0.50)	NR4A2PIM3PIM1NUDT1CREBBP
	SCHEMBL14774594	0.82	PIM3 (0.50)	NR4A2PIM3PIM1NUDT1CREBBP
	SCHEMBL2595142	0.81	AURKA (0.46)	NR4A2BRPF1KDM4EGOT1P2RX7
	SCHEMBL38662412	0.80	PIM3 (0.45)	NR4A2PIM3PIM1CREBBPKDM4E
	SCHEMBL16340090	0.79	PIM3 (0.50)	NR4A2PIM3PIM1CREBBPKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.