Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540199 | 0.80 | SPHK1 (0.35) | TGFBR1SPHK1 | |
| SCHEMBL17012567 | 0.70 | — | — | |
| SCHEMBL24851661 | 0.69 | KDM4E (0.39) | RIPK1 | |
| SCHEMBL16773934 | 0.69 | TGFBR1 (0.37) | TGFBR1SPHK1 | |
| SCHEMBL15790827 | 0.69 | — | — | |
| SCHEMBL12391339 | 0.69 | — | — | |
| SCHEMBL25678648 | 0.68 | — | — | |
| SCHEMBL24543149 | 0.68 | SPHK1 (0.36) | TGFBR1SPHK1 | |
| SCHEMBL16656709 | 0.67 | — | — | |
| SCHEMBL170982 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218826-A2 | ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS | Mersana Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |