SCHEMBL25894623

SCHEMBL25894623

CCN(C)C(=O)C(C)CCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.54
GABRP O00591 2/20 0.43
GABRD O14764 2/20 0.43
GABRA1 P14867 2/20 0.43
GABRB1 P18505 2/20 0.43
GABRG2 P18507 2/20 0.43
GABRB3 P28472 2/20 0.43
GABRA5 P31644 2/20 0.43
GABRA3 P34903 2/20 0.43
GABRA2 P47869 2/20 0.43
GABRB2 P47870 2/20 0.43
GABRA4 P48169 2/20 0.43
GABRE P78334 2/20 0.43
GABRA6 Q16445 2/20 0.43
GABRG1 Q8N1C3 2/20 0.43
GABRG3 Q99928 2/20 0.43
GABRQ Q9UN88 2/20 0.43
DPP4 P27487 2/20 0.42
DPP9 Q86TI2 2/20 0.42
FFAR4 Q5NUL3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12410076 0.81 CYP1A2 (0.60) CYP1A2GABRPGABRDGABRA1GABRB1
SCHEMBL15314151 0.81 CYP1A2 (0.60) CYP1A2GABRPGABRDGABRA1GABRB1
SCHEMBL13575653 0.78 DPP4 (0.41) CYP1A2GABRPGABRDGABRA1GABRB1
SCHEMBL19143419 0.77 LMNA (0.42) CYP1A2DPP4DPP9KDM2AHPGD
SCHEMBL14465421 0.76 HPGD (0.36) DPP4HPGD
SCHEMBL23018627 0.74 HPGD (0.35) DPP4HPGD
Trimethylammonium SCHEMBL27795883 0.74 CYP1A2 (0.86) CYP1A2GABRPGABRDGABRA1GABRB1
SCHEMBL19569730 0.72 CHRM1 (0.37) CYP1A2HDAC1HDAC2HPGD
SCHEMBL21228618 0.72 CYP1A2 (0.54) CYP1A2GABRPGABRDGABRA1GABRB1
SCHEMBL16399077 0.72 CYP1A2 (0.39) CYP1A2GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2252144-B1 USE OF ESTER AMIDES AS SOLVENTS, ESTER AMIDES AS SUCH, AND METHOD FOR PREPARING ESTER AMIDES RHODIA OPERATIONS (FR) 2023-08-02 EP disclosed