Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | MAOA | P21397 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25314598 | 0.82 | MAOA (0.45) | MAOBMAOACYP3A4SLC6A4SCN9A | |
| SCHEMBL20362209 | 0.79 | MAOA (0.50) | MAOBMAOACYP3A4SLC6A4SCN9A | |
| SCHEMBL6198163 | 0.79 | MAOA (0.50) | MAOBMAOACYP3A4SLC6A4SCN9A | |
| SCHEMBL13577090 | 0.76 | MAOA (0.50) | MAOBMAOACYP3A4SLC6A4SCN9A | |
| SCHEMBL3890960 | 0.76 | MAOB (0.50) | MAOBMAOACYP3A4SLC6A4SCN9A | |
| SCHEMBL11589995 | 0.76 | MAOB (0.50) | MAOBMAOACYP3A4SLC6A4SCN9A | |
| SCHEMBL31190642 | 0.76 | MAOA (0.46) | MAOBMAOACYP3A4SLC6A4SCN9A | |
| SCHEMBL16295776 | 0.76 | MAOB (0.47) | MAOBMAOACYP3A4SLC6A4SCN9A | |
| SCHEMBL31733523 | 0.76 | MAOB (0.47) | MAOBMAOACYP3A4SLC6A4SCN9A | |
| SCHEMBL23579567 | 0.76 | MAOB (0.77) | MAOBMAOADAOPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023127814-A1 | SUBSTITUTED QUINOLINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2023-07-06 | — | — | WO | disclosed |