Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335725 | 0.85 | DHODH (0.60) | DHODHPPARGMEN1KMT2AALDH1A1 | |
| SCHEMBL1337798 | 0.82 | DHODH (0.68) | DHODH | |
| SCHEMBL1337629 | 0.77 | DHODH (0.60) | DHODHPPARGMEN1KMT2AALDH1A1 | |
| SCHEMBL1335669 | 0.77 | DHODH (0.69) | DHODHPPARGPTPN1RXRARXRB | |
| SCHEMBL1335524 | 0.73 | DHODH (0.59) | DHODHPPARGMEN1KMT2AALDH1A1 | |
| SCHEMBL2595923 | 0.73 | DHODH (0.52) | DHODH | |
| SCHEMBL1336975 | 0.72 | DHODH (0.79) | DHODHRXRARXRB | |
| SCHEMBL1336374 | 0.71 | DHODH (0.64) | DHODHPPARGMEN1KMT2APTPN1 | |
| SCHEMBL1336938 | 0.71 | DHODH (0.59) | DHODHMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1337467 | 0.71 | DHODH (0.69) | DHODHPPARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566847-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | Icozen Therapeutics Pvt. Ltd. (IN) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138665-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-10 | — | — | WO | disclosed |