Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335438 | 0.88 | DHODH (0.66) | DHODHNR4A2NR1H4AKR1C2AKR1C1 | |
| SCHEMBL29709148 | 0.84 | DHODH (0.58) | DHODHNR4A2NR1H4AKR1C2AKR1C1 | |
| SCHEMBL12129672 | 0.84 | DHODH (0.58) | DHODHNR4A2NR1H4AKR1C2AKR1C1 | |
| SCHEMBL1337732 | 0.83 | NR1H4 (0.56) | DHODHNR4A2NR1H4PTPN11MCL1 | |
| SCHEMBL1335633 | 0.83 | DHODH (0.55) | DHODHNR4A2NR1H4PTPN11AKR1C2 | |
| SCHEMBL1337021 | 0.83 | DHODH (0.67) | DHODHNR4A2GAAL3MBTL1 | |
| SCHEMBL2595448 | 0.82 | POLB (0.48) | DHODHGAAL3MBTL1POLB | |
| SCHEMBL1337784 | 0.81 | NR1H4 (0.55) | DHODHNR4A2NR1H4PTPN11MCL1 | |
| SCHEMBL1337478 | 0.81 | DHODH (0.71) | DHODHNR4A2NR1H4AKR1C2AKR1C1 | |
| SCHEMBL1336938 | 0.79 | DHODH (0.59) | DHODHNR4A2NR1H4GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566847-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | Icozen Therapeutics Pvt. Ltd. (IN) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138665-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-10 | — | — | WO | disclosed |