Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.73 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.73 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.73 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.73 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.73 |
| ▸ | GABRP | O00591 | 4/20 | 0.69 |
| ▸ | GABRD | O14764 | 4/20 | 0.69 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.69 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.69 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.69 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.69 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.69 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.69 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.69 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.69 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.69 |
| ▸ | GABRE | P78334 | 4/20 | 0.69 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.69 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.69 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979058 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL12178039 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL16937805 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL643029 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2980777 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2981376 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2981380 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL19733059 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22449551 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL24022389 | 0.93 | MAPK1 (0.64) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566482-A1 | PROGESTERONE RECEPTOR ANTAGONISTS AND USES THEREOF | Institut National de la Santé et de la Recherche Médicale (FR) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138460-A1 | PROGESTERONE RECEPTOR ANTAGONISTS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-11-10 | — | — | WO | disclosed |