Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.73 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.73 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.73 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.73 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.73 |
| ▸ | GABRP | O00591 | 4/20 | 0.69 |
| ▸ | GABRD | O14764 | 4/20 | 0.69 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.69 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.69 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.69 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.69 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.69 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.69 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.69 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.69 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.69 |
| ▸ | GABRE | P78334 | 4/20 | 0.69 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.69 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.69 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979058 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL12178039 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL16937805 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2980777 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2981376 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2589576 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL2981380 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL19733059 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22449551 | 1.00 | GRIN1 (0.73) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL24022389 | 0.93 | MAPK1 (0.64) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | PURETECH LYT, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| EP-3087082-B1 | ATP SYNTHASE INHIBITORS AND STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AND AS POTENTIATORS FOR AMINOGLYCOSIDES AGAINST PATHOGENIC BACTERIA | SOCPRA SCIENCES ET GENIE SEC (CA) | 2023-10-11 | — | — | EP | disclosed |
| US-20220395513-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | PURETECH LYT, INC. (US) | 2022-12-15 | — | — | US | disclosed |
| US-10716797-B2 | Steroid alkaloids and compositions and kits thereof | SOCPRA SCIENCES ET GÉNIE S.E.C. (CA) | 2020-07-21 | — | — | US | disclosed |
| US-20190008875-A1 | STEROID ALKALOIDS AND COMPOSITIONS AND KITS THEREOF | UNIVERSITé DE SHERBROOKE (CA) | 2019-01-10 | — | — | US | disclosed |
| US-10137137-B2 | ATP synthase inhibitors and steroid alkaloids and uses thereof as antimicrobial agents and as potentiators for aminoglycosides against pathogenic bacteria | SOCPRA SCIENCES ET GENIE S.E.C. (CA) | 2018-11-27 | — | — | US | disclosed |
| US-20160317556-A1 | ATP SYNTHASE INHIBITORS AND STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AND AS POTENTIATORS FOR AMINOGLYCOSIDES AGAINST PATHOGENIC BACTERIA | SOCPRA SCIENCES ET GENIE S.E.C. | 2016-11-03 | — | — | US | disclosed |
| US-9090651-B2 | Helix 12 directed pharmaceutical products | ENDORECHERCHE, INC. (CA) | 2015-07-28 | — | — | US | disclosed |
| US-20130203718-A1 | PROGESTERONE RECEPTOR ANTAGONISTS AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2013-08-08 | — | — | US | disclosed |
| EP-2275109-B1 | Pregnane steroids for use in the treatment of CNS disorders | UMECRINE AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| CN-101601674-A | The pregnane steroids that is used for the treatment of the central nervous system function disorder | UMECRINE AB (SE) | 2009-12-16 | — | — | CN | disclosed |
| CN-101601675-A | The pregnane steroids that is used for the treatment of the central nervous system function disorder | UMECRINE AB (SE) | 2009-12-16 | — | — | CN | disclosed |
| CN-100518741-C | Pregnane steroids for the treatment of central nervous system disorders | UMECRINE AB (SE) | 2009-07-29 | — | — | CN | disclosed |
| EP-1704161-A1 | HELIX 12 DIRECTED STEROIDAL PHARMACEUTICAL PRODUCTS | Endorecherche, Inc. (CA) | 2006-09-27 | — | — | EP | disclosed |
| US-20050250749-A1 | Helix 12 directed pharmaceutical products | ENDORECHERCHE, INC. | 2005-11-10 | — | — | US | disclosed |
| US-20050222099-A1 | Pregnane steroids for use in the treatment of cns disorders | UMECRINE AB (SE) | 2005-10-06 | — | — | US | disclosed |
| WO-2005066194-A1 | HELIX 12 DIRECTED STEROIDAL PHARMACEUTICAL PRODUCTS | ENDORECHERCHE, INC. (CA) | 2005-07-21 | — | — | WO | disclosed |
| CN-1607954-A | Pregnane steroids for the treatment of central nervous system disorders | UMECRINE AB (SE) | 2005-04-20 | — | — | CN | disclosed |
| US-6274118-B1 | INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE | NORDION INTERNATIONAL INC. (CA) | 2001-08-14 | — | — | US | disclosed |
| WO-1995002424-A1 | LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN | NORDION INTERNATIONAL INC. (CA) | 1995-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | CYP21A2, CYP46A1, CYP17A1 | GRIN1 2519/4885GRIN2B 2012/4885GRIN2D 3231/4885 |
| US-20050250749-A1 | Helix 12 directed pharmaceutical products | SHBG, AR, NR5A1 | GRIN1 3802/4885GRIN2B 4127/4885GRIN2D 4460/4885 |
| US-20160317556-A1 | ATP SYNTHASE INHIBITORS AND STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AND AS POTENTIATORS FOR AMINOGLYCOSIDES AGAINST PATHOGENIC BACTERIA | ATP5ME, ATP5MG, ATP5F1A | GRIN1 1274/4885GRIN2B 3137/4885GRIN2D 3127/4885 |
| US-20190008875-A1 | STEROID ALKALOIDS AND COMPOSITIONS AND KITS THEREOF | ATP5ME, ATP5MG, ATP5F1A | GRIN1 2168/4885GRIN2B 3032/4885GRIN2D 4276/4885 |
| US-20220395513-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | CYP21A2, CYP46A1, CYP17A1 | GRIN1 2519/4885GRIN2B 2012/4885GRIN2D 3231/4885 |
| US-20130203718-A1 | PROGESTERONE RECEPTOR ANTAGONISTS AND USES THEREOF | PGR, PGRMC2, PGRMC1 | GRIN1 1845/4885GRIN2B 1550/4885GRIN2D 4036/4885 |
| US-10137137-B2 | ATP synthase inhibitors and steroid alkaloids and uses thereof as antimicrobial agents and as potentiators for aminoglycosides against pathogenic bacteria | ATP5ME, ATP5MG, ATP5F1A | GRIN1 1274/4885GRIN2B 3137/4885GRIN2D 3127/4885 |
| US-10716797-B2 | Steroid alkaloids and compositions and kits thereof | ATP5ME, ATP5MG, ATP5F1A | GRIN1 2168/4885GRIN2B 3032/4885GRIN2D 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.