Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726679 | 0.84 | ELANE (0.60) | ELANETAAR1LMNAUBE2NGLS | |
| SCHEMBL1514915 | 0.84 | ELANE (0.60) | ELANETAAR1UBE2NGLSF2 | |
| SCHEMBL27342474 | 0.79 | ELANE (0.56) | ELANETAAR1LMNAUBE2NGLS | |
| SCHEMBL5989502 | 0.79 | ELANE (0.73) | ELANEF2PLAU | |
| SCHEMBL14863708 | 0.79 | ELANE (0.47) | ELANELMNAF2PLAUPOLB | |
| SCHEMBL28136631 | 0.78 | ALOX15 (0.47) | ELANEF2PLAU | |
| SCHEMBL28136630 | 0.78 | ELANE (0.44) | ELANEF2PLAUPOLB | |
| SCHEMBL960949 | 0.77 | ELANE (0.62) | ELANEF2PLAU | |
| SCHEMBL2932427 | 0.77 | ELANE (0.38) | ELANETAAR1LMNAUBE2N | |
| SCHEMBL14193572 | 0.77 | ELANE (0.54) | ELANETAAR1UBE2NGLSF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933575-B | Yclohexyl-azetidinyl antagonists of CCR2 | JANSSEN PHARMACEUTICA NV | 2015-02-04 | — | — | CN | disclosed |
| EP-2566328-A1 | INDAZOLES | GlaxoSmithKline LLC (US) | 2013-03-13 | — | — | EP | disclosed |
| CN-102933575-A | Yclohexyl-azetidinyl antagonists of ccr2 | JANSSEN PHARMACEUTICA NV | 2013-02-13 | — | — | CN | disclosed |
| WO-2011140325-A1 | INDAZOLES | GLAXOSMITHKLINE LLC (US) | 2011-11-10 | — | — | WO | disclosed |