Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934802 | 0.78 | — | — | |
| SCHEMBL4119628 | 0.78 | — | — | |
| SCHEMBL19025853 | 0.76 | — | — | |
| SCHEMBL5504187 | 0.74 | — | — | |
| SCHEMBL11731891 | 0.72 | — | — | |
| SCHEMBL1933231 | 0.72 | — | — | |
| SCHEMBL3022868 | 0.72 | GABRA1 (0.54) | GABRA1GABRB2 | |
| SCHEMBL11717665 | 0.70 | IDO1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL3989123 | 0.70 | HSPA5 (0.54) | — | |
| SCHEMBL9359703 | 0.69 | GABRA1 (0.37) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563125-A1 | AZAINDOLES AS JANUS KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011137022-A1 | AZAINDOLES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-11-03 | — | — | WO | disclosed |