Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.44 |
| ▸ | TNF | P01375 | 7/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20786928 | 0.82 | HDAC3 (0.47) | HTR2AHTR2CPSMB1PSMB5TNF | |
| SCHEMBL25320411 | 0.81 | PSMB1 (0.47) | HTR2AHTR2CPSMB1PSMB5TNF | |
| SCHEMBL25320408 | 0.81 | PSMB1 (0.47) | HTR2AHTR2CPSMB1PSMB5TNF | |
| SCHEMBL20786901 | 0.80 | TNF (0.41) | HTR2AHTR2CPSMB1PSMB5TNF | |
| SCHEMBL1725380 | 0.80 | TNF (0.39) | HTR2AHTR2CPSMB1PSMB5TNF | |
| SCHEMBL20808710 | 0.79 | PSMB1 (0.41) | HTR2AHTR2CPSMB1PSMB5TNF | |
| SCHEMBL6923560 | 0.79 | GRM2 (0.55) | HTR2AHTR2CPSMB1PSMB5TNF | |
| SCHEMBL25898525 | 0.79 | HTR2C (0.40) | HTR2AHTR2CPSMB1PSMB5TNF | |
| SCHEMBL20786917 | 0.78 | HTR2A (0.52) | HTR2AHTR2CPSMB1PSMB5GRM2 | |
| SCHEMBL25897720 | 0.77 | TNF (0.35) | TNFGRM2HDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |