Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2589796 | 1.00 | MEN1 (0.68) | MEN1KMT2AALDH1A1TSHRGAA | |
| Bromide SCHEMBL11180829 | 0.98 | MEN1 (0.66) | MEN1KMT2AALDH1A1TSHRGAA | |
| Bromide SCHEMBL11277318 | 0.98 | MEN1 (0.66) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL2587982 | 0.85 | MEN1 (0.55) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL2587984 | 0.85 | MEN1 (0.55) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL4056952 | 0.83 | MEN1 (0.53) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL2586777 | 0.83 | KMT2A (0.53) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL2586772 | 0.83 | KMT2A (0.53) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL4056949 | 0.83 | MEN1 (0.53) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL14876942 | 0.83 | MEN1 (0.71) | MEN1KMT2AALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |
| EP-0023964-B1 | PHENYLIMINOTHIAZOLINE DERIVATIVES, THEIR PREPARATION AND INTERMEDIATES THEREFOR, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | disclosed |
| US-4346088-A | ANTILIPEMICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-08-24 | — | — | US | disclosed |
| EP-0023964-A1 | Phenyliminothiazoline derivatives, their preparation and intermediates therefor, pharmaceutical preparations containing them and their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-18 | — | — | EP | disclosed |