Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056949 | 1.00 | MEN1 (0.53) | MEN1KMT2AALDH1A1NPSR1GAA | |
| SCHEMBL2587982 | 0.85 | MEN1 (0.55) | MEN1KMT2AALDH1A1NPSR1GAA | |
| SCHEMBL2587984 | 0.85 | MEN1 (0.55) | MEN1KMT2AALDH1A1NPSR1GAA | |
| SCHEMBL2586777 | 0.84 | KMT2A (0.53) | MEN1KMT2AALDH1A1NPSR1GAA | |
| SCHEMBL2586772 | 0.84 | KMT2A (0.53) | MEN1KMT2AALDH1A1NPSR1GAA | |
| SCHEMBL2589796 | 0.83 | MEN1 (0.68) | MEN1KMT2AALDH1A1NPSR1GAA | |
| SCHEMBL2589792 | 0.83 | MEN1 (0.68) | MEN1KMT2AALDH1A1NPSR1GAA | |
| Bromide SCHEMBL11180829 | 0.82 | MEN1 (0.66) | MEN1KMT2AALDH1A1NPSR1GAA | |
| Bromide SCHEMBL11277318 | 0.82 | MEN1 (0.66) | MEN1KMT2AALDH1A1NPSR1GAA | |
| SCHEMBL4056197 | 0.80 | MEN1 (0.60) | MEN1KMT2AALDH1A1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |