Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22431701 | 1.00 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL17429778 | 0.85 | TSHR (0.49) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL19287592 | 0.84 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL5511480 | 0.82 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL883357 | 0.82 | SLC1A3 (0.63) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL19647227 | 0.81 | ALPI (0.52) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL31112245 | 0.81 | HPGD (0.54) | NPC1RAB9ATRPA1CYP1A2SLC15A1 | |
| SCHEMBL13545160 | 0.81 | HPGD (0.54) | NPC1RAB9ATRPA1CYP1A2SLC15A1 | |
| SCHEMBL12768183 | 0.81 | ALPI (0.52) | SLC1A3SLC1A2SLC1A1NPC1RAB9A | |
| SCHEMBL3463488 | 0.80 | SLC1A1 (0.61) | SLC1A3SLC1A2SLC1A1CYP1A2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | AR, SHBG, CYP19A1 | SLC1A3 4040/4885SLC1A2 4279/4885SLC1A1 3712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.