SCHEMBL25898750

SCHEMBL25898750

Cc1cc(-c2ccccc2)cc(N(c2ccccc2)c2ccc(-n3c4ccccc4c4ccccc43)cc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
APP P05067 2/20 0.36
HDAC4 P56524 1/20 0.35
RXFP1 Q9HBX9 1/20 0.34
TSPO P30536 1/20 0.33
KMT2A Q03164 3/20 0.33
MAPK8 P45983 1/20 0.33
IL1R1 P14778 1/20 0.33
RORC P51449 1/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HTT P42858 2/20 0.32
MAPT P10636 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19998733 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMAKR1C4AKR1C3
SCHEMBL19998889 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMAKR1C4AKR1C3
SCHEMBL19998736 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMAKR1C4AKR1C3
SCHEMBL19998730 0.92 KDM4E (0.46) L3MBTL1KDM4EATMAKR1C4AKR1C3
SCHEMBL19998883 0.92 KDM4E (0.46) L3MBTL1KDM4EATMAKR1C4AKR1C3
SCHEMBL19998732 0.92 KDM4E (0.46) L3MBTL1KDM4EATMAKR1C4AKR1C3
SCHEMBL19998757 0.92 KDM4E (0.46) L3MBTL1KDM4EATMAKR1C4AKR1C3
SCHEMBL19998891 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMAKR1C4AKR1C3
SCHEMBL13620196 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMAKR1C4AKR1C3
SCHEMBL19998886 0.91 KDM4E (0.41) L3MBTL1KDM4EATMAKR1C4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed