Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.30 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898037 | 0.77 | TAF1 (0.38) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL26800825 | 0.75 | BRD9 (0.39) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL25321710 | 0.74 | TNF (0.39) | — | |
| SCHEMBL26782296 | 0.73 | HTR2C (0.36) | — | |
| SCHEMBL25344358 | 0.72 | BRD9 (0.37) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL30550680 | 0.72 | HTR2C (0.32) | — | |
| SCHEMBL25322487 | 0.72 | HTR2C (0.32) | — | |
| SCHEMBL3577290 | 0.70 | TAF1 (0.41) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL13139309 | 0.70 | KDM4E (0.41) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL31298852 | 0.70 | GRM2 (0.40) | BRD4TAF1BRPF1CREBBPCECR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |