Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAF1 | P21675 | 2/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26800825 | 0.81 | BRD9 (0.39) | TAF1BRPF1BRD4CREBBPCECR2 | |
| SCHEMBL31298852 | 0.80 | GRM2 (0.40) | TAF1BRPF1BRD4CREBBPCECR2 | |
| SCHEMBL29026946 | 0.80 | BRD4 (0.35) | TAF1BRPF1BRD4CREBBPCECR2 | |
| SCHEMBL25899446 | 0.77 | BRD4 (0.38) | TAF1BRPF1BRD4CREBBPCECR2 | |
| SCHEMBL20752427 | 0.75 | BTK (0.47) | — | |
| SCHEMBL23706219 | 0.75 | GAA (0.37) | TAF1BRPF1BRD4CREBBPCECR2 | |
| SCHEMBL30096996 | 0.75 | GAA (0.37) | TAF1BRPF1BRD4CREBBPCECR2 | |
| SCHEMBL13061910 | 0.74 | BRD9 (0.41) | TAF1BRPF1BRD4CREBBPCECR2 | |
| SCHEMBL31364684 | 0.74 | BRD9 (0.41) | TAF1BRPF1BRD4CREBBPCECR2 | |
| SCHEMBL25898525 | 0.73 | HTR2C (0.40) | MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |