Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 20/20 | 0.63 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.53 |
| ▸ | FLT4 | P35916 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.53 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14774962 | 0.95 | CHEK1 (0.63) | CHEK1RPS6KB1FLT4FLT3RPS6KA3 | |
| SCHEMBL2589950 | 0.83 | CHEK1 (0.63) | CHEK1RPS6KB1FLT4FLT3RPS6KA3 | |
| SCHEMBL2596018 | 0.81 | CHEK1 (0.61) | CHEK1RPS6KB1FLT4FLT3RPS6KA3 | |
| SCHEMBL14774902 | 0.78 | CHEK1 (0.63) | CHEK1RPS6KB1FLT4FLT3RPS6KA3 | |
| SCHEMBL2589949 | 0.78 | CHEK1 (0.57) | CHEK1 | |
| SCHEMBL14762159 | 0.78 | CHEK1 (0.69) | CHEK1RPS6KB1FLT4FLT3RPS6KA3 | |
| SCHEMBL2595457 | 0.77 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL2596264 | 0.77 | MAPT (0.47) | — | |
| Hydrochloric Acid SCHEMBL2589889 | 0.77 | CHEK1 (0.99) | CHEK1 | |
| SCHEMBL2589894 | 0.76 | CHEK1 (1.00) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141716-A2 | PHARMACEUTICAL COMPOUNDS | SENTINEL ONCOLOGY LIMITED (GB) | 2011-11-17 | — | — | WO | disclosed |