Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.35 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | IL1B | P01584 | 2/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26184591 | 1.00 | CRBN (0.46) | CRBNDDB1IKZF1TNFIL1B | |
| SCHEMBL24192357 | 0.79 | CRBN (0.69) | CRBNDDB1IKZF1TNFIL1B | |
| SCHEMBL19503777 | 0.79 | CRBN (0.69) | CRBNDDB1IKZF1TNFIL1B | |
| SCHEMBL22892782 | 0.79 | CRBN (0.69) | CRBNDDB1IKZF1TNFIL1B | |
| SCHEMBL20975528 | 0.77 | CRBN (0.55) | CRBNDDB1IKZF1TNFIL1B | |
| SCHEMBL19503783 | 0.77 | CRBN (0.51) | CRBNDDB1IKZF1TNFIL1B | |
| SCHEMBL25898160 | 0.75 | CRBN (0.54) | CRBNDDB1IKZF1TNFIL1B | |
| SCHEMBL25898176 | 0.75 | CRBN (0.54) | CRBNDDB1IKZF1TNFIL1B | |
| SCHEMBL25567836 | 0.75 | CRBN (0.54) | CRBNDDB1IKZF1TNFIL1B | |
| SCHEMBL25876224 | 0.72 | CRBN (0.76) | CRBNDDB1IKZF1TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | AR, SHBG, CYP19A1 | CRBN 945/4885DDB1 309/4885IKZF1 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.