⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158046 | 1.00 | — | — | |
| SCHEMBL1352562 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL21427696 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL1352564 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL19905045 | 0.75 | — | — | |
| SCHEMBL19509737 | 0.75 | — | — | |
| SCHEMBL10769653 | 0.71 | — | — | |
| SCHEMBL20778126 | 0.71 | — | — | |
| SCHEMBL27612339 | 0.67 | — | — | |
| N,N-Dimethylethanaminium SCHEMBL28812589 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150612-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023141571-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2023-07-27 | — | — | WO | disclosed |