SCHEMBL2589979

SCHEMBL2589979

CCCCCCCCCCC1=CC=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.36
ESR1 P03372 2/20 0.36
ADRA2A P08913 2/20 0.36
ADORA3 P0DMS8 2/20 0.36
TACR2 P21452 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
KCNH2 Q12809 2/20 0.36
CYP3A4 P08684 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
SHBG P04278 1/20 0.36
TP53 P04637 1/20 0.36
HSPD1 P10809 1/20 0.36
ADRB3 P13945 1/20 0.36
HTR2C P28335 1/20 0.36
HSPE1 P61604 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2589096 1.00 PTGS2 (0.36) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2581422 1.00 PTGS2 (0.36) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL18166883 1.00 PTGS2 (0.36) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2586965 1.00 PTGS2 (0.36) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL1539757 1.00 PTGS2 (0.36) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL2589165 1.00 PTGS2 (0.36) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL9149230 1.00 PTGS2 (0.36) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL27832533 1.00 PTGS2 (0.36) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL9140819 0.98 PTGS2 (0.35) PTGS2ESR1ADRA2AADORA3TACR2
SCHEMBL9148846 0.98 PTGS2 (0.35) PTGS2ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975427-B2 Synthesis of alkyl cyclopentadiene compounds UNIVATION TECHNOLOGIES, LLC (US) 2015-03-10 US claimed
US-20130085289-A1 Synthesis of Alkyl Cyclopentadiene Compounds UNIVATION TECHNOLOGIES, LLC (US) 2013-04-04 US claimed
EP-2563747-A1 SYNTHESIS OF ALKYL CYCLOPENTADIENE COMPOUNDS Univation Technologies, LLC (US) 2013-03-06 EP claimed
CN-102844284-A Synthesis method of alkyl cyclopentadiene compound UNIVATION TECH LLC 2012-12-26 CN claimed
WO-2011136902-A1 SYNTHESIS OF ALKYL CYCLOPENTADIENE COMPOUNDS UNIVATION TECHNOLOGIES, LLC (US) 2011-11-03 WO claimed
EP-0441460-B1 Cyclopentadienes, their manufacture and lubricating compositions containing them PENNZOIL PROD CO (US) 1996-11-20 EP claimed
EP-0441460-A2 Cyclopentadienes, their manufacture and lubricating compositions containing them PENNZOIL PRODUCTS COMPANY (US) 1991-08-14 EP claimed
US-4849566-A Lubricants comprising novel cyclopentanes, cyclopentadienes, cyclopentenes, and mixtures thereof and methods of manufacture PENNZOIL PRODUCTS COMPANY (US) 1989-07-18 US claimed
CN-114436825-B Lead compound, preparation method and application thereof, and lubricating oil composition 中国石油化工股份有限公司 2024-12-06 CN disclosed
CN-114426900-B Lead compound, preparation method and application thereof, and lubricating oil composition 中国石油化工股份有限公司 2022-10-21 CN disclosed
CN-113388434-B Extreme pressure antiwear agent composition, extreme pressure antiwear agent and space lubricant 中国石油化工股份有限公司 2022-07-15 CN disclosed
CN-114436825-A Lead compound, preparation method and application thereof, and lubricating oil composition 中国石油化工股份有限公司 2022-05-06 CN disclosed
CN-114426900-A Lead compound, preparation method and application thereof, and lubricating oil composition 中国石油化工股份有限公司 2022-05-03 CN disclosed
CN-108348402-B Polymerizable composition based on thermally cleavable compounds 义获嘉伟瓦登特公司 2021-02-02 CN disclosed
US-4929782-A BASIC CATALYSTS, ALKYLATION, DEHYDRATION PENNZOIL PRODUCTS COMPANY (US) 1990-05-29 US disclosed
US-4849566-A Lubricants comprising novel cyclopentanes, cyclopentadienes, cyclopentenes, and mixtures thereof and methods of manufacture PENNZOIL PRODUCTS COMPANY (US) 1989-07-18 US disclosed
EP-0282579-A4 Cyclopentanes and lubricants comprising cyclopentanes. PENNZOIL PROD CO (US) 1989-04-12 EP disclosed
EP-0282579-A1 Cyclopentanes and lubricants comprising cyclopentanes. PENNZOIL PROD CO (US) 1988-09-21 EP disclosed
WO-1988001994-A1 LUBRICANTS COMPRISING NOVEL CYCLOPENTANES, CYCLOPENTADIENES, CYCLOPENTENES, AND MIXTURES THEREOF AND METHODS OF MANUFACTURE PENNZOIL PRODUCTS COMPANY (US) 1988-03-24 WO disclosed
US-4721823-A Lubricants comprising novel cyclopentanes, cyclopentadienes, cyclopentenes, and mixtures thereof and methods of manufacture PENNZOIL PRODUCTS COMPANY (US) 1988-01-26 US disclosed