SCHEMBL25900

SCHEMBL25900

Nc1ccc(N2CCC(O)CC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.55
ALDH1A1 P00352 6/20 0.55
GAA P10253 5/20 0.55
KDM4E B2RXH2 3/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
HTT P42858 2/20 0.55
KMT2A Q03164 2/20 0.55
USP2 O75604 2/20 0.55
MEN1 O00255 1/20 0.55
NPC1 O15118 1/20 0.55
TP53 P04637 1/20 0.55
POLB P06746 1/20 0.55
THRB P10828 1/20 0.55
ALOX15 P16050 1/20 0.55
RECQL P46063 1/20 0.55
RAB9A P51151 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
HSD17B10 Q99714 1/20 0.55
GFER P55789 5/20 0.53
LMNA P02545 5/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6219283 0.93 MAPT (0.58) MAPTALDH1A1GAAKDM4EL3MBTL1
SCHEMBL6258199 0.91 MAPT (0.61) MAPTALDH1A1GAAKDM4EL3MBTL1
Hydrochloric Acid SCHEMBL6220458 0.91 MAPT (0.61) MAPTALDH1A1GAAKDM4EL3MBTL1
SCHEMBL33623 0.88 AR (0.49) MAPTALDH1A1GAAKDM4EL3MBTL1
SCHEMBL853367 0.88 AR (0.49) MAPTALDH1A1GAAKDM4EL3MBTL1
SCHEMBL15650766 0.88 AR (0.49) MAPTALDH1A1GAAKDM4EL3MBTL1
SCHEMBL6253761 0.88 MAPT (0.62) MAPTALDH1A1GAAKDM4EL3MBTL1
Hydrochloric Acid SCHEMBL5393462 0.86 MAPT (0.50) MAPTALDH1A1GAAKDM4EL3MBTL1
Hydrochloric Acid SCHEMBL1154260 0.86 MAPT (0.50) MAPTALDH1A1GAAKDM4EL3MBTL1
Hydrochloric Acid SCHEMBL5406643 0.86 MAPT (0.50) MAPTALDH1A1GAAKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546359-A Method for upgrading and recycling polycaprolactone 南昌大学 2024-08-27 CN claimed
EP-3141552-B1 THIENOPYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE HANMI PHARM IND CO LTD (KR) 2019-04-17 EP claimed
US-10112954-B2 Bicyclic heteroaryl derivatives having inhibitory activity for protein kinase HANMI PHARM. CO., LTD. (KR) 2018-10-30 US claimed
EP-3141552-A1 THIENOPYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE Hanmi Pharm. Co., Ltd. (KR) 2017-03-15 EP claimed
EP-2528920-A2 BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE Hanmi Pharm. Co., Ltd. (KR) 2012-12-05 EP claimed
US-20120302567-A1 BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-29 US claimed
WO-2011093672-A2 BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE HANMI PHARM. CO., LTD. (KR) 2011-08-04 WO claimed
EP-4027995-B1 HPK1 ANTAGONISTS AND USES THEREOF NIMBUS SATURN INC (US) 2026-05-27 EP disclosed
US-12630530-B2 FGFR inhibitor compound and use thereof HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2026-05-19 US disclosed
US-12466841-B2 Substituted pyrrolo[3,4-c]pyridines as HPK1 antagonists Nimbus Saturn, Inc. (US) 2025-11-11 US disclosed
US-12466812-B2 Pyridinyltriazine derivative having protein kinase inhibitory activity, and pharmaceutical composition for preventing, ameliorating, or treating cancer comprising same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-11-11 US disclosed
EP-3965803-B1 SMALL-MOLECULE FOCAL ADHESION KINASE (FAK) INHIBITORS DANA FARBER CANCER INST INC (US) 2025-08-20 EP disclosed
US-12365696-B2 Small-molecule focal adhesion kinase (FAK) inhibitors DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-07-22 US disclosed
EP-1080092-A2 BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION WARNER-LAMBERT COMPANY (US) 2001-03-07 EP disclosed
EP-0964864-A2 PYRIDO 2,3-D] PYRIMIDINES AND 4-AMINOPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION WARNER-LAMBERT COMPANY (US) 1999-12-22 EP disclosed
WO-1999061444-A2 BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION WARNER-LAMBERT COMPANY (US) 1999-12-02 WO disclosed
WO-1998033798-A2 PYRIDO[2,3-D]PYRIMIDINES AND 4-AMINO-PYRIMIDINES AS INHIBITORS OF CELL PROLIFERATION WARNER LAMBERT COMPANY (US) 1998-08-06 WO disclosed
EP-0481299-B1 N-phenyl-piperidyl-4-amines and drugs containing them BASF AG (DE) 1994-07-20 EP disclosed
US-5260318-A Phenylpiperidylamines and drugs containing them BASF AKTIENGESELLSCHAFT (DE) 1993-11-09 US disclosed
EP-0481299-A2 N-phenyl-piperidyl-4-amines and drugs containing them BASF Aktiengesellschaft (DE) 1992-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12365696-B2 Small-molecule focal adhesion kinase (FAK) inhibitors PTK2, CTTN, TNK2 MAPT 3204/4885ALDH1A1 2836/4885GAA 2773/4885
US-12630530-B2 FGFR inhibitor compound and use thereof FGFR3, FGFR1, FGFR4 MAPT 2238/4885ALDH1A1 1323/4885GAA 2785/4885
US-20120302567-A1 BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE CDK2, SBK3, CDK2AP1 MAPT 1332/4885ALDH1A1 3711/4885GAA 1653/4885
US-10112954-B2 Bicyclic heteroaryl derivatives having inhibitory activity for protein kinase CDK2, SBK3, CDK2AP1 MAPT 1332/4885ALDH1A1 3711/4885GAA 1653/4885
US-12466841-B2 Substituted pyrrolo[3,4-c]pyridines as HPK1 antagonists PDXK, HIPK1, HIPK3 MAPT 3393/4885ALDH1A1 4707/4885GAA 2502/4885
US-12466812-B2 Pyridinyltriazine derivative having protein kinase inhibitory activity, and pharmaceutical composition for preventing, ameliorating, or treating cancer comprising same FGFR3, FGFR1, FGFR4 MAPT 2488/4885ALDH1A1 2136/4885GAA 4556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.