SCHEMBL2590143

SCHEMBL2590143

CCCC[C@]1(CC)CS(=O)(=O)c2cc(CNC(CC(=O)OC)CC(=O)OC)c(OC)cc2C(c2ccccc2)N1

nearest known ligand 0.90

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2592666 1.00 SLC10A2 (0.90) SLC10A2
SCHEMBL2590845 1.00 SLC10A2 (0.90) SLC10A2
SCHEMBL2581899 0.97 SLC10A2 (0.90) SLC10A2
SCHEMBL2589730 0.95 SLC10A2 (0.86) SLC10A2
Linerixibat SCHEMBL2579144 0.95 SLC10A2 (1.00) SLC10A2
Linerixibat SCHEMBL2584943 0.95 SLC10A2 (1.00) SLC10A2
Linerixibat SCHEMBL2586025 0.95 SLC10A2 (1.00) SLC10A2
SCHEMBL2590146 0.92 SLC10A2 (0.77) SLC10A2
SCHEMBL2592663 0.92 SLC10A2 (0.77) SLC10A2
SCHEMBL2588927 0.92 SLC10A2 (0.81) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2563122-A1 CHEMICAL COMPOUNDS Glaxosmithkline LLC (US) 2013-03-06 EP disclosed
WO-2011137135-A1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE LLC (US) 2011-11-03 WO disclosed