Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.84 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25902156 | 0.93 | NLRP3 (0.81) | NLRP3MAPTSMN1; SMN2HPGDTHRB | |
| SCHEMBL25902235 | 0.91 | NLRP3 (1.00) | NLRP3MAPTSMN1; SMN2HPGDTHRB | |
| SCHEMBL25902140 | 0.84 | NLRP3 (0.79) | NLRP3MAPTSMN1; SMN2HPGDTHRB | |
| SCHEMBL25902147 | 0.84 | NLRP3 (0.80) | NLRP3MAPTSMN1; SMN2HPGDTHRB | |
| SCHEMBL25902137 | 0.83 | NLRP3 (0.82) | NLRP3MAPTSMN1; SMN2HPGDTHRB | |
| SCHEMBL25902153 | 0.83 | NLRP3 (0.78) | NLRP3MAPTSMN1; SMN2HPGDTHRB | |
| SCHEMBL25902128 | 0.81 | NLRP3 (0.85) | NLRP3MAPTSMN1; SMN2HPGDTHRB | |
| SCHEMBL25902226 | 0.81 | NLRP3 (0.73) | NLRP3MAPTSMN1; SMN2HPGDTHRB | |
| SCHEMBL25902126 | 0.81 | NLRP3 (0.84) | NLRP3MAPTSMN1; SMN2HPGDTHRB | |
| SCHEMBL25902237 | 0.80 | NLRP3 (0.87) | NLRP3SMN1; SMN2HPGDTHRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137885-A1 | COMPOUND HAVING PYRIDOIMIDAZOLE AS PARENT NUCLEUS, AND PREPARATION METHOD FOR AND USE OF COMPOUND | 中国药科大学 | 2023-07-27 | — | — | WO | disclosed |