Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 7/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516524 | 0.89 | SMYD2 (0.41) | SMYD2SMN1; SMN2RIPK1CYP3A4HTT | |
| SCHEMBL4516522 | 0.89 | SMYD2 (0.41) | SMYD2SMN1; SMN2RIPK1CYP3A4HTT | |
| SCHEMBL1150304 | 0.84 | SMYD2 (0.38) | SMYD2KLK7KLK5PDK4GPR119 | |
| SCHEMBL1150302 | 0.84 | SMYD2 (0.38) | SMYD2KLK7KLK5PDK4GPR119 | |
| SCHEMBL16584506 | 0.84 | SMYD2 (0.38) | SMYD2KLK7KLK5PDK4GPR119 | |
| SCHEMBL28717400 | 0.82 | GLA (0.38) | GLASMN1; SMN2GAA | |
| SCHEMBL554798 | 0.80 | IL1B (0.38) | SMYD2KLK7GPR119KDM4EPKM | |
| SCHEMBL554334 | 0.80 | IL1B (0.38) | SMYD2KLK7GPR119KDM4EPKM | |
| SCHEMBL554333 | 0.80 | IL1B (0.38) | SMYD2KLK7GPR119KDM4EPKM | |
| SCHEMBL30742967 | 0.80 | SMYD2 (0.38) | SMYD2PDK4GPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |