Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748110 | 0.82 | CHRM1 (0.49) | HSD17B10CHRM1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL23396470 | 0.82 | HSD17B10 (0.47) | HSD17B10ACECHRM1KMT2AGAA | |
| SCHEMBL16748058 | 0.82 | HSD17B10 (0.71) | HSD17B10CHRM1SIGMAR1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8934375 | 0.81 | HSD17B10 (0.69) | HSD17B10CHRM1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL10168635 | 0.77 | CDK4 (0.48) | ACEKMT2A | |
| SCHEMBL6164614 | 0.76 | HDAC8 (0.64) | — | |
| SCHEMBL7567649 | 0.76 | HDAC8 (0.64) | — | |
| SCHEMBL7566120 | 0.76 | HDAC8 (0.64) | — | |
| SCHEMBL16745497 | 0.76 | HCRTR1 (0.55) | HSD17B10CHRM1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL17169777 | 0.75 | ACE (0.71) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | AR, SHBG, CYP19A1 | HSD17B10 93/4885ACE 1203/4885CHRM1 3890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.