Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25315575 | 0.83 | — | — | |
| SCHEMBL25903505 | 0.80 | TDP1 (0.43) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17052958 | 0.75 | CA1 (0.34) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL26029317 | 0.74 | NR5A1 (0.41) | LTA4HNPC1LMNATP53CYP1A2 | |
| SCHEMBL17918919 | 0.73 | LTA4H (0.41) | LTA4HKMT2AMEN1L3MBTL1PLK1 | |
| SCHEMBL26254910 | 0.73 | LTA4H (0.41) | LTA4HKMT2AMEN1L3MBTL1PLK1 | |
| SCHEMBL1697679 | 0.71 | SMN1; SMN2 (0.42) | LTA4HKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL12523720 | 0.71 | KDM4E (0.36) | L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26022244 | 0.69 | TDP1 (0.40) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10158177 | 0.69 | CA12 (0.42) | LTA4HL3MBTL1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |