Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.60 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22077731 | 0.85 | S1PR1 (0.59) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22074487 | 0.85 | S1PR1 (0.56) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22077851 | 0.84 | S1PR1 (0.55) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL25904004 | 0.83 | S1PR1 (0.60) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22074485 | 0.82 | S1PR1 (0.61) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL25904640 | 0.82 | S1PR1 (0.59) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22077168 | 0.82 | S1PR1 (0.64) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22077844 | 0.81 | S1PR1 (0.58) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL23915869 | 0.81 | S1PR1 (0.57) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22074444 | 0.81 | S1PR1 (0.57) | S1PR1S1PR4S1PR5ADORA3S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125397-A1 | PREPARATION METHOD FOR AROMATIC RING DERIVATIVE FOR IMMUNE REGULATION | 上海济煜医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |