Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25904145 | 0.83 | CNR1 (0.40) | KDM4EHSD17B10KIF11MAPTCNR1 | |
| SCHEMBL25904123 | 0.82 | KDM4E (0.38) | KDM4EHSD17B10KIF11MAPTCNR1 | |
| SCHEMBL25904471 | 0.80 | PDE3B (0.40) | KDM4EKIF11JUNNFKB1NFKB2 | |
| SCHEMBL25904390 | 0.78 | CNR1 (0.40) | KDM4ECNR1JUNNFKB1NFKB2 | |
| SCHEMBL25904479 | 0.77 | PARP10 (0.43) | KDM4EKIF11CNR1JUNNFKB1 | |
| SCHEMBL18980661 | 0.75 | AR (0.58) | KDM4EHSD17B10KIF11CNR1AR | |
| SCHEMBL29722191 | 0.75 | AR (0.58) | KDM4EHSD17B10KIF11CNR1AR | |
| SCHEMBL19785361 | 0.73 | PDE2A (0.52) | MAPT | |
| SCHEMBL16110649 | 0.73 | AR (0.47) | AR | |
| SCHEMBL8872828 | 0.73 | MAPT (0.64) | KDM4EHSD17B10KIF11MAPTJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147513-A2 | COMPOSITIONS OF AUTOPHAGY MODULATING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2023-08-03 | — | — | WO | disclosed |