Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25904123 | 0.87 | KDM4E (0.38) | CNR1PDE3BPDE3AKDM4EMEN1 | |
| SCHEMBL25904124 | 0.83 | KDM4E (0.43) | CNR1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL25903699 | 0.83 | PDE3B (0.55) | PDE3BPDE3AKDM4EMEN1KMT2A | |
| SCHEMBL25904479 | 0.82 | PARP10 (0.43) | CNR1PDE3BPDE3AKDM4ECYP3A4 | |
| SCHEMBL25904763 | 0.80 | MEN1 (0.58) | PDE3BPDE3AKDM4EMEN1KMT2A | |
| SCHEMBL25904390 | 0.80 | CNR1 (0.40) | CNR1PDE3BPDE3AKDM4E | |
| SCHEMBL25903697 | 0.77 | PDE3B (0.56) | PDE3BPDE3AKDM4EMEN1KMT2A | |
| SCHEMBL25904296 | 0.77 | MAP2 (0.41) | PDE3BPDE3AMEN1KMT2ARXFP1 | |
| SCHEMBL25904471 | 0.77 | PDE3B (0.40) | PDE3BPDE3AKDM4EKIF11 | |
| SCHEMBL25905198 | 0.77 | PDE3B (0.41) | PDE3BPDE3AMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147513-A2 | COMPOSITIONS OF AUTOPHAGY MODULATING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2023-08-03 | — | — | WO | disclosed |