Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 12/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26658767 | 1.00 | TIPARP (0.44) | TIPARPKITFLT3GRM4ROCK2 | |
| SCHEMBL25904908 | 0.95 | TIPARP (0.44) | TIPARPKITFLT3GRM4TNKS | |
| SCHEMBL25904910 | 0.95 | TIPARP (0.44) | TIPARPKITFLT3GRM4TNKS | |
| SCHEMBL25904816 | 0.94 | TIPARP (0.42) | TIPARPKITFLT3GRM4ROCK2 | |
| SCHEMBL26658718 | 0.93 | TIPARP (0.46) | TIPARPKITFLT3GRM4METAP2 | |
| SCHEMBL25320275 | 0.92 | TIPARP (0.50) | TIPARPKITFLT3GRM4ROCK2 | |
| SCHEMBL25903612 | 0.92 | TIPARP (0.50) | TIPARPKITFLT3GRM4ROCK2 | |
| SCHEMBL30550654 | 0.92 | TIPARP (0.50) | TIPARPKITFLT3GRM4ROCK2 | |
| SCHEMBL25903730 | 0.92 | TIPARP (0.50) | TIPARPKITFLT3GRM4ROCK2 | |
| SCHEMBL26658809 | 0.90 | TIPARP (0.44) | TIPARPKITFLT3GRM4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |